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                                       6407 Southwest Blvd, Fort Worth, Texas  817-731-9198  

 Allergy Asthma Sinusitis

 

     

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We have several clinical trials in allergy and asthma you might consider  Call Diana Jones RN at 817-731-9198

ALERT ALERT ALERT ALERT

 

NEW TIP: Before your turn your heater on …..

 

It’s going to get cool before long ( believe it or not) It seems that when the furnace is fired up for the first several times in the heating season, the mold and algae burn off which have been growing on the coils. This brown choking cloud of dust usually rolls out when you are asleep- you may never notice it- but you’ll have coughing and irritation for days afterwards.   For those with allergies or a possibly compromised respiratory tract, this could pose a problem.

 

What's a person to do? Well, Dr. Bob suggests taping a product such as Swiffer® refills over the vents to your bedroom at least. This product is  electrostatically-charged, meaning it is better able to pick up more of the dust, dirt, hair, and common allergens than traditional methods, but also traps more airborne particles on the cloth when taped over the registers. The suggested retail price for a pack of 64 Swiffers is around $11, but if you check at places such as Sam's Club, Lowe's, Home Depot, and others, you might find a deal on them.   To tape the cloths to the registers, you can use masking tape, but there's another product I found information on. It is called Intertape Pro-Mask Blue Painter's Tape®. While it is more expensive than the old light tan masking tape, it is a high-tack tape is perfect for masking delicate areas such as wallpaper, painted surfaces, and glass. Removes easily without leaving a sticky residue.

 

Top Stories in the news from the American College of Allergy Asthma and Immunology

Exercise-induced asthma rate high among college athletes
One in three college athletes may have exercise-induced asthma, despite no previous history of the disease, according to a study in
Medicine & Science in Sports & Exercise.Scientists at Ohio State University studied 107 athletes, using eucapnic voluntary hyperpnea testing. The test challenges or stresses the lungs by making the subject hyperventilate, then measuring his or her lung function to determine if it decreases from the stress, mimicking the expected changes in exercise-induced asthma. Forty-two tested positive for exercise-induced asthma, 36 of which had no previous history of asthma. Researchers found that neither gender nor the sport they participated in affected the likelihood of testing positive.

Women’s allergic conditions don't affect their fertility
Women with asthma, eczema or hay fever are not less fertile than women without the conditions, according to a study in the American Journal of Epidemiology. Researchers at the University of Nottingham, in the United Kingdom, say women with these allergic diseases may even be slightly more likely to have children. They compared fertility rates among 491,516 women who were 15 to 44 years old during a 10-year period. Among the women, 13 percent had asthma, 14 percent had eczema, and 12 percent had hay fever. However, researchers found no significant difference in fertility rates between women with and without asthma, eczema or hay fever. And, 20-something women with asthma actually had slightly higher fertility rates than the same age group without asthma. 

Record number of U.S. doses ready for next flu season
Flu vaccine manufacturers say they will have a record 132 million doses ready for the United States’ 2007-2008 flu season, and potentially more if a fifth company obtains U.S. approval, according to officials at the U.S. Centers for Disease Control and Prevention. CDC guidelines, which have recently expanded to cover more age groups, call for 218 million Americans to get vaccinated, so the estimated supply will still fall short. The estimates were announced at a recent gathering of flu vaccine manufacturers, health care providers, and public health officials.

Chitin enzyme may explain some asthma flares
Chitin, the compound that gives shellfish their protective shell and invertebrates their inner frame, may be what triggers some patient’s asthma, according to a study in Nature. Scientists at the University of California, San Francisco, built on previous animal studies that linked asthma symptoms and chitin reactions. In mice, they discovered chitin triggered an allergic inflammatory response in the lungs, as well as increased chitinase, an enzyme produced by cells in the lungs that fights chitin. The researchers are currently trying to determine the effectiveness at breaking down chitin among the different versions of chitinase that humans have due to genetic differences.
 

April 11

New procedure smooths muscle in asthma patients’ airways
A bronchoscopic procedure, called bronchial thermoplasty, which uses radio waves to smooth overgrown muscle in the airways, improved moderate to severe asthma patients’ asthma control, according to a study in the New England Journal of Medicine. Scientists randomly assigned 112 subjects with moderate to severe asthma to either three thermoplasty sessions or their usual drug treatment. At 1 year, morning peak expiratory flow was better in patients receiving thermoplasty — 39 liters per minute vs. 8.5 liters per minute for those receiving usual treatment. The thermoplasty group also reported more symptom-free days (40 vs. 17), fewer asthma symptoms and fewer puffs of rescue medication. The procedure is not yet approved by the U.S. Food and Drug Administration.

Mediterranean diet may lower children’s allergic disease risk
A diet high in fruits, vegetables and nuts, commonly referred to as a Mediterranean diet, could lessen children’s risk of allergic disease and asthma, according to a study in Thorax. Scientists at the National Heart and Lung Institute, London, studied 690 children, from 7 to 18 years old, in rural Crete, a Greek island. Parents filled out questionnaires about respiratory and allergic symptoms, as well as a 58-item food frequency questionnaire. The children also underwent skin prick tests for 10 common aeroallergens. Children who ate a Mediterranean diet, as measured by 12 dietary items, were a third less likely to have allergic rhinitis. Eating margarine more than doubled the risk of both wheeze and atopy.

Chlorine pools increase workers’ lung problems
People who spend a lot of time near chlorinated pools have a higher risk of breathing problems, according to a study in European Respiratory Journal. Researchers at University of Utrecht in The Netherlands surveyed 624 swimming pool employees, measured air quality at six pools, and measured trichloramine — the most irritating type of chlorine byproduct chloramine — levels at all 38 pools included in the study. Compared with pool employees with the least exposure to trichloramines, swimming instructors had a 2.4-fold greater risk of frequent sinusitis or sore throat and a 3.4-fold greater risk of chronic cold.

 

Aspirin linked to asthma prevention in men
An analysis of data from a study investigating aspirin’s role in preventing first heart attacks suggests aspirin may reduce new-onset asthma risk in adult males, according to a report in the American Journal of Respiratory and Critical Care Medicine. Researchers at Brigham and Women's Hospital, Boston, retrospectively analyzed The Physicians' Health Study, which randomized 22,071 healthy male physicians, from 40 to 84 years old, to aspirin or placebo. Subjects answered questionnaires that included information about asthma diagnosis at baseline, six months and annually thereafter. The subjects who took 325 mg of aspirin every other day had 22-percent less risk of new onset asthma. The potential protective effect was not affected by baseline risk factors such as age, body mass index, or smoking. And the protection also was greater among younger men.


Study: Children with asthma can reliably report own health status
Children as young as 7 years old can dependably report on their asthma health status, according to a study in Pediatrics. Scientists at the American Academy of Pediatrics, Elk Grove Village, Ill., interviewed 414 parents and children separately, using the Children's Health Survey Asthma-Child Version (CHSA-C) to measure physical health, activities and emotional health. The children ranged from 7 to 16 years old, with a mean age of 11.5. The scientists evaluated the data reported by the children for reliability based on internal consistency and test-retest, for validity by comparison to symptoms and lung function, and for feasibility reflected by completion time and missing data. Reliability estimates for the activities and emotional health scales were in the acceptable (at least .70) range in all but one category. Internal consistency ratings were acceptable in five of nine age groups. Test-retest correlations were high for all age groups and increased with child age. 

Six-shot series has promise for ragweed allergy sufferers
A new treatment of six weekly shots may offer relief from ragweed allergy symptoms for more than a year, according to a small randomized, double-blind, placebo-controlled study published in The New England Journal of Medicine. Researchers at Johns Hopkins Asthma and Allergy Center in Baltimore studied 25 subjects who reported ragweed allergic problems each fall season. The series of shots, called AIC, which stands for Amb a 1-immunostimulatory oligodeoxyribonucleotide conjugate, produced more than 1 year of relief for 14 subjects. In addition, subjects who received the treatment reported fewer hay fever symptoms and a better quality of life and used less allergy medication than volunteers who received six placebo shots. A larger study seeking to enroll 140 volunteers is under way. (WE ARE DOING THESE STUDIES) mor Study: Allergic rhinitis affects sleep quality
Physicians should be aware of the close relationship between allergic rhinitis and sleep disorders,  more

Law moves decongestants behind the counter nationwide
Following similar state laws, as of Sept. 30, new federal restrictions will require stores to move decongestants behind the pharmacy counter or in a locked case, making it harder for Americans to access the medicines.. moree

Early fungal exposure may increase allergy risk
Infants exposed to airborne fungal spores Penicillium and Aspergillus may be at higher risk of developing non-fungal allergies, according to a study in Pediatric Allergy and Immunologymore

Asthmatic smokers can improve lung function quickly by quitting
Smokers who have asthma and quit smoking can realize more than 15 percent improvement in lung function tests in less than two months\ more

Introducing grains later increases wheat allergy risk
Delaying the introduction of cereal grains until after 6 months old increases the risk of wheat allergy. more

Inhaled corticosteroids may boost cataract risk in elderly  more
 FDA: Antihistamine linked to breathing problems, death
 Phenergan, should not be used for children younger than two years old because of possible breathing problems.  more



Preschoolers in day care at higher risk for allergy symptoms
 
more

Nurses, printers, woodworkers have higher asthma risk
Nurses, printers and woodworkers have an increased risk of developing asthma, possibly due to exposure to substances at work, according to a study in The Lancet. A team of European scientists analyzed health information and details about workplace exposure for more than 6,800 subjects who participated in the European Community Respiratory Health Survey between 1990 and 1995. None of the subjects had asthma when the study began. The team analyzed exposure to potentially asthma-causing substances using information from asthma experts. Exposure to substances known to cause occupational asthma on average increased the risk of asthma by 60 percent. Highest-risk jobs were printing (137 percent), nursing (122 percent) and woodworking (122 percent). Fires, chemical spills and other such incidents tripled subjects’ asthma risk.

Teens with poorly controlled asthma
like electronic disease management
Adolescents with poorly controlled asthma may benefit from using the Web and instant messaging to manage their disease, according to a study in Chest. Scientists at Leiden University Medical Center in the Netherlands enrolled 97 adolescents to electronically monitor their asthma daily for one month, including entering lung function data at a Web site or via instant message. Subjects received feedback about their lung function so they could react to changes and optimize their asthma control. Researchers then held focus groups with 35 study subjects. Among subjects with poor asthma control, 65 percent were able and ready to incorporate Internet-based asthma self-management, compared with only 11 percent of subjects with good asthma control.

High-intensity warm ups may help exercisers with asthma
A small study by researchers at Indiana University in Bloomington says recreational athletes with asthma may be able to reduce airway tightening during physical activity by starting with short, high-intensity warm ups. To investigate whether such repeat warm-ups could improve exercise-induced bronchoconstriction (EIB) without drugs, researchers enrolled eight moderately trained athletes with documented EIB to exercise on a treadmill under four different conditions. With no warm up, the subjects’ lung capacity was reduced by about 18 percent. After running at peak speed eight times for 30 seconds with 45-second rests between intervals, lung capacity was reduced by 9 percent, slightly less than the 10-percent drop defining EIB. After taking 200 micrograms of salbutamol, lung capacity rose by 9 percent with no warm up and 15 percent with the high-intensity warm ups.


 This site accepts no sponsorship or advertisement and is totally funded by Lanier Education and Research Network 

 

   Cutting edge therapy for allergy, asthma, and recurrent infection

Is allergy involved in your asthma ?  ( you bet.  In over 90% of asthma – allergy is a issue)  Waiting to outgrow it ?  ( so is granny)

Sick and tired of allergy? 

  Click for your options

 RUSH Immunotherapy  get it over quicker? We have a vast experience   Click  here for the facts and precautions

  You’ll find the answer to questions by clicking here  Click here for the questionaire you need to fill out  if you are coming in for a new patient visit for Hives or swelling   

      Chronic Cough  

                                            HEADACHES? Use this thirty question test to get started with your doctor – print it out

Drainage”  Even if you don’t have heartburn – you MAY have gastroesophageal refluxclick here 

Sinus infections?   This is the work-up

Polyps – uh oh Click here for the latest news

 NEW: Online textbook of allergy from the American Academy of Allergy Asthma and Immunology, The Allergy Report
 

 


Xolair for doctors and patients

commonly asked questions and practical answers on Xolair            ( Omalizumab)  from an experience of hundreds of patients – and contact with hundred of doctors who prescribe Xolair. This is not a company site.

Xolair ( Omalizumab) in asthma

Xolair  ( Omalizumab) in allergy

Xolair  ( Omalizumab)in pregnancy

Xolair  ( Omalizumab) doses, pricing/ unknowns

 

Dr. Lanier and Dr. Chang’’s textbook chapter on Xolair ( Omalizumab)  ( Blaiss editor)

 

Dr. Lanier and Dr. Chang’s Textbook chapter on Xolair( Omalizumab) ( Lieberman)

 

Dr. Lanier’s Allergy Proceedings on Unanswered Questions about anti-IgE ( Omalizumab)

 

Dr. Lanier’s Symposia for World Allergy Organization Journal on the Possible Risks of Xolair ( Omalizumab)

 

Dr. Lanier’s “Risks of Xolair

( Omalizumab) with Parasites

 

Dr. Lanier’s Risk of anaphylaxis on allergy shots while taking Xolair

( Omalizumab) abstract

 

Dr. Lanier’s observation of Fluctuating IgE levels in patients treated with Omalizumab

 

XOLAIR WARNING.

 The FDA has announced that it had requested Genentech, Inc. to add a boxed warning to the product label for Xolair. The boxed warning emphasizes that Xolair may cause a severe allergic reaction after any dose of Xolair, even if there was no reaction to the first dose. Also, severe allergic reactions after administration of Xolair may be delayed up to 24 hours after the dose is given. The FDA cautions health care providers should be prepared to manage life-threatening severe allergic reactions following Xolair administration and observe patients for at least two hours after an injection. Following administration of Xolair, patients should also carry and know how to initiate emergency self-treatment for anaphylaxis. To view the FDA news release, click on this link or copy and paste it into your web browser:

 

   http://www.fda.gov/bbs/topics/NEWS/2007/NEW01567.html 


 Obesity, asthma association stronger in non-allergic women
Obese women with no allergy history are at greater risk for asthma than obese men with no allergy history, according to a study in Chest. Scientists at the University of Ottawa studied a cross-sectional survey of 86,144 Canadian adults. Obese women had an adjusted odds ratio for asthma of 1.85, relative to women who weren’t obese. The obese men had an adjusted odds ratio for asthma of 1.21. According to the authors, “One unit of increased BMI was associated with an approximate 6 percent increase in asthma risk in women, and 3 percent in men.” The association was even stronger among obese, non-allergic women. They had a 9.5 percent asthma risk, relative to 3.1 percent for non-allergic women who weren’t obese.  more

Migraines common among allergic rhinitis sufferers
Many people with allergic rhinitis also suffer from migraine headaches,.  more

Early fish consumption may lower allergy risk
Children who eat fish before 1 year of age may have a decreased risk of developing asthma and allergic disease, more 

Asthma, allergic disease among kids increasing worldwide
The number of children with asthma and other allergic diseases is on the rise worldwide, more 

Study: Early asthma prevention for at-risk kids unsuccessful
 modified early exposure to house dust mites and increased omega-3 fatty acid intake do not prevent asthma in children with family history of the disease.. more
Asthmatics decreasing prescription use early in pregnancy
A large number of women significantly reduce their asthma medication use early in their pregnancies, putting themselves and their babies at risk,.  more

 Obesity may have bigger affect on pregnancy than asthma
Complications of pregnancy among obese women with asthma may have more to do with obesity than with asthma. more

Cat dander may bother patients with other allergies
Patients with allergies to mold, dust mites or timothy grass might also be affected by cat dander, even if they aren’t specifically allergic to cats, according to a study in the American Journal of Respiratory and Critical Care Medicine. Researchers from several organizations in Europe analyzed cross-sectional data from 1,884 participants at 20 centers in the European Community Respiratory Health Survey, which measured house dust mite and cat allergen in mattress dust samples, and IgE sensitization to four allergens. They found higher bronchial responsiveness when exposed to cat dander in research subjects who weren't allergic to cats, but were sensitive to three other common allergens: dust mites, mold or timothy grass. The authors concluded, "cat allergen exposure at moderate levels may be harmful to all atopic adults." 

Vitamin C, omega-3s may lower asthma risk
A teenager’s adequate intake of vitamin C and omega-3 fatty acids may promote respiratory health and lessen the effects of oxidative stress, according to a study in
Chest. Researchers at the Harvard School of Public Health in Boston, the U.S. EPA and Health Canada studied 2,112 12th-grade students from 13 areas in the United States and Canada during the 1998-99 school year, assessing associations between diet, pulmonary function and respiratory symptoms. The researchers found that those who consumed less than one-quarter of a serving of fruit a day had lower average lung-function scores. Those who took in less than 5.2 milligrams a day of vitamin E had an increased risk of reported asthma. And taking in less than 22 milligrams per day of omega-3 fatty acids was associated with increased risk of chronic bronchitis, wheezing and asthma.

Supplemental selenium doesn’t improve asthma
Supplementing with selenium doesn’t appear to have clinical benefit in adults with asthma, according to a study in Thorax, even though selenium levels tend to be low among that population. Researchers at Imperial College London tested 197 adults from London with asthma, randomly assigning subjects to receive for 24 weeks either a yeast and selenium (100 micrograms daily) preparation or yeast-only placebo. Subjects receiving the selenium preparation had a 48-percent increase in blood levels of selenium during the trial. However, while some indicators of asthma severity improved more in the selenium group than in the placebo group, the difference was not statistically significant. 

AMA votes to lobby for laws allowing
anaphylaxis treatment drugs at school
Delegates at the American Medical Association recently voted at its annual policy meeting to lobby for laws allowing severely allergic children to bring lifesaving drugs to school. The new policy refers to drugs including prescription epinephrine and other injectable medicines that treat severe allergic reactions. The policy also urges schools to develop preparedness plans for handling severe allergic reactions and ensuring that all affected children have an individual emergency care plan. 

Five percent in U.S. report food allergies
More than 5 percent of U.S. adults may have food allergies, according to a study in the Journal of Allergy and Clinical Immunology. Researchers at the Food and Drug Administration used data from a 2001 national survey. About half of those with food allergies reported being allergic to at least one of the eight most common food allergens: milk and other dairy foods; fish; eggs; crustaceans, such as lobster and shrimp; tree nuts, such as walnuts; peanuts; soy; and wheat. Among those who read food labels, 40 percent reported “serious” or “very serious” difficulty trying to protect themselves. However, since the survey was administered, new legislation that went into effect in 2006 now requires food makers to list the eight most common food allergens in plain English.

 

 

               FDA Alert on Advair / Foradil/ Serevent with patient suggestions  ……..

Alert for Asthmatics using Advair / Foradil / Serevent / Symbicort

What happened: On Nov. 18, 2005, the Food and Drug Administration (FDA) issued a public health advisory for asthma medications containing a long acting beta agonist       ( Serevent in Advair  or Fomoterol in Foradil and Symbicort ).   The FDA states the medications may increase the risk of severe asthma episodes and possibly death, if a severe asthma episode occurs. The asthma medications included in the advisory are: Advair Diskus, Foradil Aerolizer and Serevent Diskus and Symbicort.  In its advisory, the FDA said that although the components including Long acting beta agents decrease how often asthma attacks occur, they may make the attacks that do do occur more severe. On 2 March 06, the FDA and Glaxo released a medication guide for patients which can be accessed at http://www.fda.gov/cder/foi/label/2006/021077s028mg.pdf    ( here is a summary)

  • long acting beta agonist should be used only if other medicines don't control your asthma.
  • If you are using a Advair, don't stop using it until you've talked with me.

What do practicing doctors feel about this: I attended the recent American Academy of Allergy asthma and Immunology annual meeting, studied the issue in some depth and talked with many scientists and FDA representatives.  While the overwhelming majority of the doctors there feel the advisory will not change their prescribing of Advair,  I personally will change my prescribing habits.

What does this mean to you?: I will require before refilling your prescription for Advair that you read the medication guide and are aware of the issue.  If you want to save time and effort, you can click on "I have read the medication guide - I understand the issues and want to continue"  You may also choose - I am using Advair but want to safely see if there is a way to change my asthma medications. If you choose this option, you may be asked to schedule a regular appointment for a quick check of your lung functions ( don't use Advair that morning).  You will also be given a short five question survey called the "Asthma Control Test".  If you want to change, we will prescribe a different medication ( a single type of medication) and repeat the process in one month to make sure your transition is easy and safe. 

DON'T STOP TAKING ADVAIR / SYMBICORT ABRUPTLY - THAT COULD BE HAZARDOUS.

 


 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

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